How to make qualitative judgment by using the selectivity of liquid chromatograph detector

The same detector of the liquid chromatograph has different response values ​​for different types of compounds, and the detectors of different liquid chromatographs have different responses to the same compound.
The same detector of the liquid chromatograph has different response values ​​for different types of compounds, and the detectors of different liquid chromatographs have different responses to the same compound. Therefore, when a certain test compound is detected by two or more detectors at the same time, the ratio of detection sensitivity of the two detectors or two or more detectors to the test compound is closely related to the properties of the test compound. It can be used to qualitatively analyze the test compound. This is the basic principle of the dual detector qualitative system.
As a liquid chromatograph double detector system, the connection is generally divided into two ways of series connection and parallel connection. When one of the two detectors of the chromatograph is non-destructive, a simple series connection can be used by connecting the non-destructive detector in series before the destructive detector. If both detectors are destructive, they need to be connected in parallel by connecting a three-way connected to the two detectors at the outlet end of the column. The dual detection systems most commonly used for qualitative identification in liquid chromatography are UV detectors and fluorescence detectors.

The above is summarized by the Liquid Chromatography Division of Shandong Luchuang Analytical Instrument Co., Ltd., and I hope that it will help you to use the liquid chromatograph correctly. If you have any technical problems, please log in to http://Online Consultation Luchuang Analysis Chromatography engineer.
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