Although the human genome sequence has been sequenced, human studies of the mechanism of action of genes are still hindered because most genes are not isolated. Finland researchers have isolated and cloned an important class of protein kinase genes from the human genome. These genes are closely related to many cell signal transduction processes by phosphorylating and regulating other proteins. It is estimated that about 1/4 of the kinases play a role in the pathogenesis of human cancer. The report showed that the team further used high-throughput screening of protein kinases using the cloned kinase genome and obtained two new kinases. One function is to regulate the "Robinia pseudoacacia" signal pathway, which is closely related to many types of human cancers; the other new kinase is related to the role of Kaposi's sarcoma herpes virus. The head of the research group, Professor Yusi Tepaler of the University of Helsinki in Finland, stated: “The many kinase genes we have isolated will eventually form a gene bank that can analyze the role of kinase signals in different cellular disease patterns for future systems. This lays the foundation. Moreover, kinases can also serve as targets for drug treatment. By understanding kinases, humans can deal with a wide range of cancers." Barbecue wire Grill Grate is made of high quality 304 stainless steel, never rusting and durable. BBQ Wire mesh does not have any coating or chemical ingredients, making food safer. BBQ Grate,BBQ Mesh,BBQ Grill, grill grate,grill mesh Shenzhen Lanejoy Technology Co.,LTD , https://www.baking-rack.com
A Finnish team cloned almost all possible human functional protein kinase genes and cloned a series of correspondingly inactive catalytic kinases that can be used to perform functional studies of protein kinases. The research results were published in the recent "Cell" magazine.
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Finland clones human key genome